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Adjusting to a new depression medication

When you start a new antidepressant medication, keep in mind that your body needs a little time to adjust. Patients are often instructed to start a new medication at a low dosage; the doctor then adjusts the dosage until reaching a level he or she feels will work best for the patient. This "adjustment" process is sometimes referred to as "titration," and is a common approach for starting on most antidepressants.

Some people may experience symptoms such as dizziness or nausea (see Common Side Effects of Antidepressants) during this adjustment period. It's perfectly normal and usually only lasts for a short time.

Talk with your doctor about how you’re responding to your new treatment for depression. Your doctor will help you know what to expect from your particular antidepressant medication.

You or your family should call your doctor right away if you have worsening depression, thoughts of suicide, or sudden or severe changes in mood or behavior, especially when starting a new antidepressant or after a change in dose. You should not stop taking your antidepressant without first discussing this with your doctor.